Dre Hasna Bouchaab

Médecin associée
Service d'oncologie médicale
Département d'oncologie UNIL CHUV

Contacter par mail
+41 79 556 8437

Spécialisations

Cancers du thorax

Domaines d'intérêt académique et/ou clinique

Traitement et immunotherapie pour les cancers pulmonaires

Publications scientifiques sélectionnées

2024

A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy.

Huber F, Arnaud M, Stevenson BJ, Michaux J, Benedetti F, Thevenet J, Bobisse S, Chiffelle J, Gehert T, Müller M, Pak H, Krämer AI, Altimiras ER, Racle J, Taillandier-Coindard M, Muehlethaler K, Auger A, Saugy D, Murgues B, Benyagoub A, Gfeller D, Laniti DD, Kandalaft L, Rodrigo BN, Bouchaab H, Tissot S, Coukos G, Harari A, Bassani-Sternberg M

Nat Biotechnol. 2024 Oct 11

Sustained Clinical Benefit and Intracranial Activity of Tarlatamab in Previously Treated Small Cell Lung Cancer: DeLLphi-300 Trial Update.

Dowlati A, Hummel HD, Champiat S, Olmedo ME, Boyer M, He K, Steeghs N, Izumi H, Johnson ML, Yoshida T, Bouchaab H, Borghaei H, Felip E, Jost PJ, Gadgeel S, Chen X, Yu Y, Martinez P, Parkes A, Paz-Ares L

J Clin Oncol. 2024 Oct 10;42(29):3392-3399

Pathology of Surgically Resected Lung Cancers Following Neoadjuvant Therapy.

Berezowska S, Keyter M, Bouchaab H, Weissferdt A

Adv Anat Pathol. 2024 Sep 1;31(5):324-332

A pharmacist-led interprofessional medication adherence program improved adherence to oral anticancer therapies: The OpTAT randomized controlled trial.

Bandiera C, Cardoso E, Locatelli I, Zaman K, Diciolla A, Digklia A, Stravodimou A, Cristina V, Aedo-Lopez V, Dolcan A, Sarivalasis A, Bouchaab H, Pasquier J, Dotta-Celio J, Peters S, Wagner D, Csajka C, Schneider MP

PLoS One. 2024;19(6):e0304573

[Management of bone metastasis in non-small cell lung cancer].

Apeiranthiti A, Vanniere F, Bayoumy K, Christofis M, Serena A, Mosimann V, Abdelhamid K, Papadopoulos S, Nguyen-Ngoc T, Bouchaab H, Peters S, Mederos N

Rev Med Suisse. 2024 May 15;20(874):973-977

Long-Term Results of Stereotactic Radiotherapy in Patients with at Least 10 Brain Metastases at Diagnosis.

Kinj R, Hottinger AF, Böhlen TT, Ozsahin M, Vallet V, Dunet V, Bouchaab H, Peters S, Tuleasca C, Bourhis J, Schiappacasse L

Cancers (Basel). 2024 Apr 29;16(9)

[Oncology: what's new in 2023].

Jankovic J, Abdelhamid K, Berthold D, Desbaillets N, Bouchaab H, Dei Tos G, Demicheli R, Diciolla A, Digklia A, Ferraro DA, Florez L, Galli-Vareia I, Hottinger A, Latifyan S, Liapi A, Mederos N, Giacomuzzi Moore B, Sakr R, Stamatiou A, Wagner AD, Peters S, Sarivalasis A, Vanniere F, Zaman K, Stravodimou A

Rev Med Suisse. 2024 Jan 17;20(856-7):80-87

Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural carcinosis.

Chriqui LE, Abdelnour-Berchtold E, Zanfrini E, Devesa-Perez S, Gonzalez M, Krueger T, Ellefsen K, Destaillats A, Bonnet D, Hübner M, Bouchaab H, Bassani-Sternberg M, Peters S, Cavin S, Perentes JY

Cancer Treat Res Commun. 2024;42:100858

2023

[Oncology: what's new in 2022].

Nguyen-Ngoc T, Abdelhamid K, Degrauwe N, Galland S, Serena A, Christofis M, Mederos N, Bouchaab H, Diciolla A, Dris N, Orcurto A, Perrinjaquet C, Schnetz M, Latifyan S, Wetterwald L, Herrera Gómez RG, Cristina V, Sarivalasis A, Michielin O, Berthold D, Digklia A, Wagner AD, Zaman K, Peters S, Stravodimou A

Rev Med Suisse. 2023 Jan 18;19(N° 809-10):52-57

2022

A differential process mining analysis of COVID-19 management for cancer patients.

Cuendet MA, Gatta R, Wicky A, Gerard CL, Dalla-Vale M, Tavazzi E, Michielin G, Delyon J, Ferahta N, Cesbron J, Lofek S, Huber A, Jankovic J, Demicheli R, Bouchaab H, Digklia A, Obeid M, Peters S, Eicher M, Pradervand S, Michielin O

Front Oncol. 2022;12:1043675

Systematic comparison with autoimmune liver disease identifies specific histological features of immune checkpoint inhibitor-related adverse events.

Coukos A, Vionnet J, Obeid M, Bouchaab H, Peters S, Latifyan S, Wicky A, Michielin O, Chtioui H, Moradpour D, Fasquelle F, Sempoux C, Fraga M

J Immunother Cancer. 2022 Oct;10(10)

[Targeted therapies and non-small cell carcinomas : novelties].

Stauber R, Gro S L, Nguyen-Ngoc T, Mederos N, Bouchaab H, Peters S, Abdelhamid K

Rev Med Suisse. 2022 May 18;18(782):970-975

Humoral Responses Against Variants of Concern by COVID-19 mRNA Vaccines in Immunocompromised Patients.

Obeid M, Suffiotti M, Pellaton C, Bouchaab H, Cairoli A, Salvadé V, Stevenel C, Hottinger R, Pythoud C, Coutechier L, Molinari L, Trono D, Ribi C, Gottardo R, Fenwick C, Pascual M, Duchosal MA, Peters S, Pantaleo G

JAMA Oncol. 2022 May 1;8(5):e220446

Delayed Diagnosis of Lung Carcinoma Presenting as Choroidal Metastasis in a COVID-19 Patient and Initially Treated with Osimertinib.

Haeller CN, Khamsy L, Kloepper J, Schiappacasse L, Bouchaab H, Peters S, Schalenbourg A

Klin Monbl Augenheilkd. 2022 Apr;239(4):586-589

[2021 Oncology update].

Meyer ML, Chrysou K, Stamatiou A, Gilabert M, Herrera Gomez RG, Latifyan S, Masmoudi S, Mederos N, Perrinjaquet C, Berthold D, Bouchaab H, Cristina V, Digklia A, Michielin O, Orcurto A, Sarivalasis A, Stravodimou A, Wagner AD, Zaman K, Peters S, Jankovic J

Rev Med Suisse. 2022 Feb 2;18(767):182-186

2021

Early discharge after thoracoscopic anatomical pulmonary resection for non-small-cell lung cancer.

Forster C, Perentes JY, Ojanguren A, Abdelnour-Berchtold E, Zellweger M, Bouchaab H, Peters S, Krueger T, Gonzalez M

Interact Cardiovasc Thorac Surg. 2021 Nov 22;33(6):892-898

Is sleeve lobectomy safe after induction therapy?-a systematic review and meta-analysis.

Chriqui LE, Forster C, Lovis A, Bouchaab H, Krueger T, Perentes JY, Gonzalez M

J Thorac Dis. 2021 Oct;13(10):5887-5898

(68)Ga-DOTATOC PET/CT to detect immune checkpoint inhibitor-related myocarditis.

Boughdad S, Latifyan S, Fenwick C, Bouchaab H, Suffiotti M, Moslehi JJ, Salem JE, Schaefer N, Nicod-Lalonde M, Costes J, Perreau M, Michielin O, Peters S, Prior JO, Obeid M

J Immunother Cancer. 2021 Oct;9(10)

Optimizing Oral Targeted Anticancer Therapies Study for Patients With Solid Cancer: Protocol for a Randomized Controlled Medication Adherence Program Along With Systematic Collection and Modeling of Pharmacokinetic and Pharmacodynamic Data.

Bandiera C, Cardoso E, Locatelli I, Digklia A, Zaman K, Diciolla A, Cristina V, Stravodimou A, Veronica AL, Dolcan A, Sarivalasis A, Liapi A, Bouchaab H, Orcurto A, Dotta-Celio J, Peters S, Decosterd L, Widmer N, Wagner D, Csajka C, Schneider MP

JMIR Res Protoc. 2021 Jun 29;10(6):e30090

[Telephone follow-up of SARS-CoV-2 positive patients at the Oncology Department of Lausanne University Hospital].

Jankovic J, Da Silva Lopes AM, Morez A, Darnac C, Demicheli R, Dalla-Vale M, Lauriers N, Garcia Sanchez J, Bouchaab H, Ninane F, Peters S, Michielin O, Pradervand S, Eicher M, Colomer-Lahiguera S

Rev Med Suisse. 2021 Apr 7;17(733):703-707

Stereotactic lung reirradiation for local relapse: A case series.

Kinj R, Casutt A, Bennassi A, Bouchaab H, Vallet V, Lovis A, Ozsahin M

Clin Transl Radiat Oncol. 2021 May;28:85-87

Personalized Cytokine-Directed Therapy With Tocilizumab for Refractory Immune Checkpoint Inhibitor-Related Cholangiohepatitis.

Moi L, Bouchaab H, Mederos N, Nguyen-Ngoc T, Perreau M, Fenwick C, Vaucher J, Sempoux C, Peters S, Obeid M

J Thorac Oncol. 2021 Feb;16(2):318-326

[2020 oncology update].

Dei Tos G, Galli Vareia I, Huber A, Wolf B, Diciolla A, Herrera Gomez RG, Wagner D, Digklia A, Bouchaab H, Cristina V, Stravodimou A, Zaman K, Sarivalasis A, Berthold D, Peters S, Perrinjaquet C, Kloepper J, Jankovic J

Rev Med Suisse. 2021 Jan 27;17(723):201-205

Impact of an enhanced recovery after surgery pathway on thoracoscopic lobectomy outcomes in non-small cell lung cancer patients: a propensity score-matched study.

Forster C, Doucet V, Perentes JY, Abdelnour-Berchtold E, Zellweger M, Faouzi M, Bouchaab H, Peters S, Marcucci C, Krueger T, Rosner L, Gonzalez M

Transl Lung Cancer Res. 2021 Jan;10(1):93-103

Abscopal effect in a patient with malignant pleural mesothelioma treated with palliative radiotherapy and pembrolizumab.

Mampuya WA, Bouchaab H, Schaefer N, Kinj R, La Rosa S, Letovanec I, Ozsahin M, Bourhis J, Coukos G, Peters S, Herrera FG

Clin Transl Radiat Oncol. 2021 Mar;27:85-88

2020

Outcomes with immune checkpoint inhibitors for relapsed small-cell lung cancer in a Swiss cohort.

Schmid S, Mauti LA, Friedlaender A, Blum V, Rothschild SI, Bouchaab H, Frösch P, Britschgi C, König D, Wannesson L, Janthur WD, Schär S, Demmer I, Addeo A, Jochum W, Früh M

Cancer Immunol Immunother. 2020 Aug;69(8):1605-1613

ESMO Management and treatment adapted recommendations in the COVID-19 era: Lung cancer.

Passaro A, Addeo A, Von Garnier C, Blackhall F, Planchard D, Felip E, Dziadziuszko R, de Marinis F, Reck M, Bouchaab H, Peters S

ESMO Open. 2020 Jun;5(Suppl 3)

[Small-cell lung cancer: management and novelties].

Abdelhamid K, Kakourou A, Degrauwe N, Nikolopoulou A, Bouchaab H, Peters S, Nguyen-Ngoc T, Mederos N

Rev Med Suisse. 2020 May 27;16(695):1079-1085

Relationship between pneumonitis induced by immune checkpoint inhibitors and the underlying parenchymal status: a retrospective study.

Pozzessere C, Bouchaab H, Jumeau R, Letovanec I, Daccord C, Bourhis J, Prior JO, Peters S, Lazor R, Beigelman-Aubry C

ERJ Open Res. 2020 Jan;6(1)

2019

Curative management of a cardiac metastasis from lung cancer revealed by an electrical storm.

Jumeau R, Vincenti MG, Pruvot E, Schwitter J, Vallet V, Zeverino M, Moeckli R, Bouchaab H, Bourhis J, Ozsahin M

Clin Transl Radiat Oncol. 2020 Mar;21:62-65

[The new management options for lung cancer in the immunotherapy era].

Meganem H, Socianu RM, Bouchaab H, Mederos N, Nguyen-Ngoc T, Peters S, Dolcan A

Rev Med Suisse. 2019 May 15;15(651):1032-1037

Preoperative chemotherapy and radiotherapy concomitant to cetuximab in resectable stage IIIB NSCLC: a multicentre phase 2 trial (SAKK 16/08).

Curioni-Fontecedro A, Perentes JY, Gelpke H, Xyrafas A, Bouchaab H, Mach N, Matzinger O, Stojcheva N, Frueh M, Weder W, Cathomas R, Gargiulo P, Bubendorf L, Pless M, Betticher D, Peters S, Swiss Group of Clinical Cancer Research (SAKK)

Br J Cancer. 2019 May;120(10):968-974

[Oncology, what's new in 2018].

Latifyan S, Kakourou A, Ozdemir B, Zaman K, Vernadou A, Berthold D, Abdelhamid K, Bouchaab H, Peters S, Montemurro M, Aedo V, Michielin O, Zimmermann S, Stravodimou A

Rev Med Suisse. 2019 Jan 9;15(N° 632-633):78-81

2018

Pembrolizumab as Palliative Immunotherapy in Malignant Pleural Mesothelioma.

Metaxas Y, Rivalland G, Mauti LA, Klingbiel D, Kao S, Schmid S, Nowak AK, Gautschi O, Bartnick T, Hughes BG, Bouchaab H, Rothschild SI, Pavlakis N, Wolleb S, Petrausch U, O'Byrne K, Froesch P, Löffler-Baumann M, Pratsch-Peter S, Russell P, Mingrone W, Savic S, Thapa B, Früh M, Pless M, von Moos R, John T

J Thorac Oncol. 2018 Nov;13(11):1784-1791

Immunotherapy: a new standard of care in thoracic malignancies? A summary of the European Respiratory Society research seminar of the Thoracic Oncology Assembly.

Costantini A, Grynovska M, Lucibello F, Moisés J, Pagès F, Tsao MS, Shepherd FA, Bouchaab H, Garassino M, Aerts JGJV, Mazières J, Mondini M, Berghmans T, Meert AP, Cadranel J

Eur Respir J. 2018 Feb;51(2)

2016

[Subsolid pulmonary nodules].

Keller D, Beigelman-Aubry C, Letovanec I, Bouchaab H, Gonzalez M, Lovis A, Nicod LP, Lazor R

Rev Med Suisse. 2016 Nov 16;12(539):1976-1982

Efficacy and safety of helical tomotherapy with daily image guidance in anal canal cancer patients.

De Bari B, Jumeau R, Bouchaab H, Vallet V, Matzinger O, Troussier I, Mirimanoff RO, Wagner AD, Hanhloser D, Bourhis J, Ozsahin EM

Acta Oncol. 2016 Jun;55(6):767-73

2015

BRAF Alterations as Therapeutic Targets in Non-Small-Cell Lung Cancer.

Nguyen-Ngoc T, Bouchaab H, Adjei AA, Peters S

J Thorac Oncol. 2015 Oct;10(10):1396-403

2014

Pulmonary sarcoid-like granulomatosis after multiple vaccinations of a long-term surviving patient with metastatic melanoma.

Bordry N, Costa-Nunes CM, Cagnon L, Gannon PO, Abed-Maillard S, Baumgaertner P, Murray T, Letovanec I, Lazor R, Bouchaab H, Rufer N, Romano E, Michielin O, Speiser DE

Cancer Immunol Res. 2014 Dec;2(12):1148-53