Fabio CANDOTTI, M.D.
Associate Professor of Medicine
Head Physicien
Education:
October 1987: Medical Degree, University of Brescia, Italy
Specialty Certification:
October 1996: Pediatric Allergy and Immunology Subspecialty Board, University of Brescia, Italy
June 1992: Pediatrics Specialty Board, University of Pavia, Italy
Postgraduate Training:
1994 – 1996: Postdoctoral Fellow, Clinical Gene Therapy Branch, NHGRI, NIH, Bethesda, MD, USA
1992 – 1994: Postdoctoral Fellow, Metabolism Branch, NCI, NIH, Bethesda, MD, USA
1991 – 1992: Postdoctoral Fellow, Laboratory of Biotechnology, University of Brescia, Italy
Faculty Appointments:
2014 – present: Associate Professor of Medicine, School of Medicine and Biology, University of Lausanne, Switzerland
2004 – 2014: Senior Investigator (tenured), NHGRI, NIH, Bethesda, MD, USA
1998 – 2004: Investigator (tenure-track), NHGRI, NIH, Bethesda, MD, USA
1996 – 1997: Assistant Professor, Department of Pediatrics, University of Brescia, Italy
Medical Appointments:
2017 – present: Head Physician, Division of Immunology and Allergy, CHUV, Lausanne, Switzerland
2014 – 2017: Attending Physician, Division of Immunology and Allergy, CHUV, Lausanne, Switzerland
1998 – 2014: Attending Physician, Clinical Center, NIH, Bethesda, MD, USA
1988 – 1989: Medical Second Lieutenant, Italian Customs Service Academy, Bergamo, Italy
1996 – 1997: Attending Physician, Department of Pediatrics, Brescia City Hospital, Italy
Selected Academic Administrative Appointments:
2016 – present: Chair Scientific Committee, Master in advanced Studies in Vaccinology (IMVACC), University of Lausanne, Switzerland
2014 – present: Director, Vaccine and Immunotherapy Center, CHUV, Lausanne, Switzerland
2006 – 2014: Chair, NHGRI/NIH Institutional Review Board
Selected Scientific Activity in Academic Societies:
American Society of Gene Therapy (ASGT) |
Member, Board of Directors,2010-2013 Chair, Committee on Gene & Cell Therapy of Genetic & Metabolic Diseases, 2009-10 |
Clinical Immunology Society (CIS) |
Chair, Membership Committee, 2006-2009 |
American Society of Hematology |
Chair, Immunology and Host Defense Scientific Committee (2012) |
European Society for Immunodeficiencies (ESID) |
Treasurer and Member, Executive Committee (2016-2020) |
Cooper AR, Lill GR, Shaw K, Carbonaro-Sarracino DA, Davila A, Sokolic R, Candotti F, Pellegrini M, Kohn DB
Blood. 2017 May 11;129(19):2624-2635
Shaw KL, Garabedian E, Mishra S, Barman P, Davila A, Carbonaro D, Shupien S, Silvin C, Geiger S, Nowicki B, Smogorzewska EM, Brown B, Wang X, de Oliveira S, Choi Y, Ikeda A, Terrazas D, Fu PY, Yu A, Fernandez BC, Cooper AR, Engel B, Podsakoff G, Balamurug
J Clin Invest. 2017 May 1;127(5):1689-1699
Ikawa Y, Uchiyama T, Jagadeesh GJ, Candotti F
Gene Ther. 2016 Nov;23(11):815-818
Volpi S, Santori E, Abernethy K, Mizui M, Dahlberg CI, Recher M, Capuder K, Csizmadia E, Ryan D, Mathew D, Tsokos GC, Snapper S, Westerberg LS, Thrasher AJ, Candotti F, Notarangelo LD
Blood. 2016 Jan 14;127(2):216-20
Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F
J Exp Med. 2015 Jul 27;212(8):1185-202
Ikawa Y, Hess R, Dorward H, Cullinane AR, Huizing M, Gochuico BR, Gahl WA, Candotti F
Mol Genet Metab. 2015 Jan;114(1):62-5
Sadhukhan S, Sarkar K, Taylor M, Candotti F, Vyas YM
J Immunol. 2014 Jul 1;193(1):150-60
Simon KL, Anderson SM, Garabedian EK, Moratto D, Sokolic RA, Candotti F
J Allergy Clin Immunol. 2014 Mar;133(3):896-9.e4
Candotti F, Shaw KL, Muul L, Carbonaro D, Sokolic R, Choi C, Schurman SH, Garabedian E, Kesserwan C, Jagadeesh GJ, Fu PY, Gschweng E, Cooper A, Tisdale JF, Weinberg KI, Crooks GM, Kapoor N, Shah A, Abdel-Azim H, Yu XJ, Smogorzewska M, Wayne AS, Rosenblatt
Blood. 2012 Nov 1;120(18):3635-46
Uchiyama T, Adriani M, Jagadeesh GJ, Paine A, Candotti F
Mol Ther. 2012 Jun;20(6):1270-9
Kesserwan C, Sokolic R, Cowen EW, Garabedian E, Heselmeyer-Haddad K, Lee CC, Pittaluga S, Ortiz C, Baird K, Lopez-Terrada D, Bridge J, Wayne AS, Candotti F
J Allergy Clin Immunol. 2012 Mar;129(3):762-769.e1
Shimizu M, Nikolov NP, Ueno K, Ohta K, Siegel RM, Yachie A, Candotti F
Clin Immunol. 2012 Feb;142(2):160-6
Sokolic R, Maric I, Kesserwan C, Garabedian E, Hanson IC, Dodds M, Buckley R, Issekutz AC, Kamani N, Shaw K, Tan B, Bali P, Hershfield MS, Kohn DB, Wayne AS, Candotti F
Blood. 2011 Sep 8;118(10):2688-94
Adriani M, Jones KA, Uchiyama T, Kirby MR, Silvin C, Anderson SM, Candotti F
Blood. 2011 Jun 16;117(24):6608-11
Taylor MD, Sadhukhan S, Kottangada P, Ramgopal A, Sarkar K, D'Silva S, Selvakumar A, Candotti F, Vyas YM
Sci Transl Med. 2010 Jun 23;2(37):37ra44
Davis BR, Yan Q, Bui JH, Felix K, Moratto D, Muul LM, Prokopishyn NL, Blaese RM, Candotti F
Clin Immunol. 2010 Apr;135(1):72-83
Bosticardo M, Ghosh A, Du Y, Jenkins NA, Copeland NG, Candotti F
Mol Ther. 2009 Nov;17(11):1910-8
Lagresle-Peyrou C, Six EM, Picard C, Rieux-Laucat F, Michel V, Ditadi A, Demerens-de Chappedelaine C, Morillon E, Valensi F, Simon-Stoos KL, Mullikin JC, Noroski LM, Besse C, Wulffraat NM, Ferster A, Abecasis MM, Calvo F, Petit C, Candotti F, Abel L, Fisc
Nat Genet. 2009 Jan;41(1):106-11
Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL
Clin Immunol. 2007 Jul;124(1):41-8
Konno A, Kirby M, Anderson SA, Schwartzberg PL, Candotti F
Int Immunol. 2007 Feb;19(2):185-92
Engel BC, Podsakoff GM, Ireland JL, Smogorzewska EM, Carbonaro DA, Wilson K, Shah A, Kapoor N, Sweeney M, Borchert M, Crooks GM, Weinberg KI, Parkman R, Rosenblatt HM, Wu SQ, Hershfield MS, Candotti F, Kohn DB
Blood. 2007 Jan 15;109(2):503-6
Wada T, Schurman SH, Jagadeesh GJ, Garabedian EK, Nelson DL, Candotti F
Blood. 2004 Sep 1;104(5):1270-2
Bosticardo M, Witte I, Fieschi C, Novelli F, Casanova JL, Candotti F
Mol Ther. 2004 Jun;9(6):895-901
Konno A, Wada T, Schurman SH, Garabedian EK, Kirby M, Anderson SM, Candotti F
Blood. 2004 Jan 15;103(2):676-8
Wada T, Konno A, Schurman SH, Garabedian EK, Anderson SM, Kirby M, Nelson DL, Candotti F
J Clin Invest. 2003 May;111(9):1389-97
Muul LM, Tuschong LM, Soenen SL, Jagadeesh GJ, Ramsey WJ, Long Z, Carter CS, Garabedian EK, Alleyne M, Brown M, Bernstein W, Schurman SH, Fleisher TA, Leitman SF, Dunbar CE, Blaese RM, Candotti F
Blood. 2003 Apr 1;101(7):2563-9
Wada T, Jagadeesh GJ, Nelson DL, Candotti F
Hum Gene Ther. 2002 Jun 10;13(9):1039-46
Otsu M, Hershfield MS, Tuschong LM, Muul LM, Onodera M, Ariga T, Sakiyama Y, Candotti F
Hum Gene Ther. 2002 Feb 10;13(3):425-32
Frucht DM, Gadina M, Jagadeesh GJ, Aksentijevich I, Takada K, Bleesing JJ, Nelson J, Muul LM, Perham G, Morgan G, Gerritsen EJ, Schumacher RF, Mella P, Veys PA, Fleisher TA, Kaminski ER, Notarangelo LD, O'Shea JJ, Candotti F
Genes Immun. 2001 Dec;2(8):422-32
Wada T, Schurman SH, Otsu M, Garabedian EK, Ochs HD, Nelson DL, Candotti F
Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8697-702
Otsu M, Sugamura K, Candotti F
Blood. 2001 Mar 15;97(6):1618-24
Otsu M, Sugamura K, Candotti F
Hum Gene Ther. 2000 Sep 20;11(14):2051-6
Chinnasamy D, Chinnasamy N, Enriquez MJ, Otsu M, Morgan RA, Candotti F
Blood. 2000 Aug 15;96(4):1309-16
Otsu M, Anderson SM, Bodine DM, Puck JM, O'Shea JJ, Candotti F
Mol Ther. 2000 Feb;1(2):145-53
Candotti F, Oakes SA, Johnston JA, Giliani S, Schumacher RF, Mella P, Fiorini M, Ugazio AG, Badolato R, Notarangelo LD, Bozzi F, Macchi P, Strina D, Vezzoni P, Blaese RM, O'Shea JJ, Villa A
Blood. 1997 Nov 15;90(10):3996-4003
Taylor N, Candotti F, Smith S, Oakes SA, Jahn T, Isakov J, Puck JM, O'Shea JJ, Weinberg K, Johnston JA
J Biol Chem. 1997 Mar 14;272(11):7314-9
Oakes SA, Candotti F, Johnston JA, Chen YQ, Ryan JJ, Taylor N, Liu X, Hennighausen L, Notarangelo LD, Paul WE, Blaese RM, O'Shea JJ
Immunity. 1996 Dec;5(6):605-15
Candotti F, Oakes SA, Johnston JA, Notarangelo LD, O'Shea JJ, Blaese RM
J Exp Med. 1996 Jun 1;183(6):2687-92
Candotti F, Johnston JA, Puck JM, Sugamura K, O'Shea JJ, Blaese RM
Blood. 1996 Apr 15;87(8):3097-102