Sepsis project

Sepsis is a life-threatening syndrome defined by a dysregulated response to an infection. Our group works on accelerated detection of patients with sepsis, both through the development of new molecular biomarkers and the development of integrated pattern recognition with artificial intelligence.

Selected publications

Swiss Sepsis National Action Plan: A coordinated national action plan to stop sepsis-related preventable deaths and to improve the support of people affected by sepsis in Switzerland.

Schlapbach LJ, Zimmermann EA, Meylan S, Stocker M, Suter PM, Jakob SM, National Action Plan Working Group OBOTSS. Front Med (Lausanne). 2023 Feb 20;10:1114546. doi: 10.3389/fmed.2023.1114546. eCollection 2023. PMID: 36891186. View article

ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol.

Kotsaki A, Pickkers P, Bauer M, Calandra T, Lupse M, Wiersinga WJ, Meylan S, Bloos F, van der Poll T, Slim MA, van Mourik N, Müller MCA, van Vught L, Vlaar APJ, de Nooijer A, Bakkerus L, Weis S, Antonakos N, Netea MG, Giamarellos-Bourboulis EJ. BMJ Open. 2022 Dec 20;12(12):e067251. doi: 10.1136/bmjopen-2022-067251. PMID: 36600424. View article

An Early Warning Score to predict ICU admission in COVID-19 positive patients.

Meylan S, Akrour R, Regina J, Bart PA, Dami F, Calandra T. J Infect. 2020 Nov;81(5):816-846. doi: 10.1016/j.jinf.2020.05.047. Epub 2020 May 28. PMID: 32474038.View article

Team

Jérémie Despraz (Visiting scholars)
Raphael Matusiak (Visiting scholars)
Snezana Nektarijevic (Visiting scholars)
Valentina Gandola (Masters)
Vincent Jendly (étudiant en thèse MD)

Open positions

Data manager - 80 % : application link

CHUV
Service des maladies infectieuses
Rue du Bugnon 46
CH-1011 Lausanne, Vaud, Suisse
+41 21 314 1010

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Last updated on 02/07/2024 at 14:42

Dr Syvlain Meylan

Sepsis project