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Publications choisies
The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug f
Ahmad A, Vieira JC, de Mello AH, de Lima TM, Ariga SK, Barbeiro DF, Barbeiro HV, Szczesny B, Törö G, Druzhyna N, Randi EB, Marcatti M, Toliver-Kinsky T, Kiss A, Liaudet L, Salomao R, Soriano FG, Szabo C
Pharmacol Res. 2019 May 6:104263
Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial.
Poli EC, Alberio L, Bauer-Doerries A, Marcucci C, Roumy A, Kirsch M, De Stefano E, Liaudet L, Schneider AG
Crit Care. 2019 Apr 3;23(1):108
Intravenous zanamivir for influenza myocarditis and enteral malabsorption.
Jahns FP, Ben-Hamouda N, Kirsch M, Roumy A, Liaudet L
Crit Care. 2018 Dec 4;22(1):332
Experimental ex vivo lung perfusion with sevoflurane: effects on damaged donor lung grafts.
Wang X, Parapanov R, Francioli C, Perentes JY, Letovanec I, Gonzalez M, Kern C, Ris HB, Piquilloud L, Marcucci C, Krueger T, Liaudet L, Gronchi F
Interact Cardiovasc Thorac Surg. 2018 Jun 1;26(6):977-984
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.
Berger NA, Besson VC, Boulares AH, Bürkle A, Chiarugi A, Clark RS, Curtin NJ, Cuzzocrea S, Dawson TM, Dawson VL, Haskó G, Liaudet L, Moroni F, Pacher P, Radermacher P, Salzman AL, Snyder SH, Soriano FG, Strosznajder RP, Sümegi B, Swanson RA, Szabo C
Br J Pharmacol. 2018 Jan;175(2):192-222
Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia.
Francioli C, Wang X, Parapanov R, Abdelnour E, Lugrin J, Gronchi F, Perentes J, Eckert P, Ris HB, Piquilloud L, Krueger T, Liaudet L
PLoS One. 2017;12(3):e0173916
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis.
Mukhopadhyay P, Horváth B, Rajesh M, Varga ZV, Gariani K, Ryu D, Cao Z, Holovac E, Park O, Zhou Z, Xu MJ, Wang W, Godlewski G, Paloczi J, Nemeth BT, Persidsky Y, Liaudet L, Haskó G, Bai P, Boulares AH, Auwerx J, Gao B, Pacher P
J Hepatol. 2017 Mar;66(3):589-600
Natriuretic Peptide Receptor B modulates the proliferation of the cardiac cells expressing the Stem Cell Antigen-1.
Rignault-Clerc S, Bielmann C, Liaudet L, Waeber B, Feihl F, Rosenblatt-Velin N
Sci Rep. 2017 Feb 9;7:41936
Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation.
Lee WS, Erdelyi K, Matyas C, Mukhopadhyay P, Varga ZV, Liaudet L, Haskú G, Čiháková D, Mechoulam R, Pacher P
Mol Med. 2016 Sep;22:136-146
Pharmacological Reconditioning of Marginal Donor Rat Lungs Using Inhibitors of Peroxynitrite and Poly (ADP-ribose) Polymerase During Ex Vivo Lung Perfusion.
Wang X, Wang Y, Parapanov R, Abdelnour E, Gronchi F, Perentes JY, Piquilloud L, Ris HB, Letovanec I, Liaudet L, Krueger T
Transplantation. 2016 Jul;100(7):1465-73
Pharmacological Therapy in the Heart as an Alternative to Cellular Therapy: A Place for the Brain Natriuretic Peptide?
Rosenblatt-Velin N, Badoux S, Liaudet L
Stem Cells Int. 2016;2016:5961342
Drug-induced mitochondrial dysfunction and cardiotoxicity.
Varga ZV, Ferdinandy P, Liaudet L, Pacher P
Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1453-67
Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse.
Parapanov R, Lugrin J, Rosenblatt-Velin N, Feihl F, Waeber B, Milano G, Vergely C, Li N, Pacher P, Liaudet L
Clin Sci (Lond). 2015 Jul;129(2):187-98
Poly(ADP-ribose) polymerases as modulators of mitochondrial activity.
Bai P, Nagy L, Fodor T, Liaudet L, Pacher P
Trends Endocrinol Metab. 2015 Feb;26(2):75-83
Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy.
Varga ZV, Giricz Z, Liaudet L, Haskó G, Ferdinandy P, Pacher P
Biochim Biophys Acta. 2015 Feb;1852(2):232-42
Cutting edge: IL-1α is a crucial danger signal triggering acute myocardial inflammation during myocardial infarction.
Lugrin J, Parapanov R, Rosenblatt-Velin N, Rignault-Clerc S, Feihl F, Waeber B, Müller O, Vergely C, Zeller M, Tardivel A, Schneider P, Pacher P, Liaudet L
J Immunol. 2015 Jan 15;194(2):499-503
Cannabidiol Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis.
Hao E, Mukhopadhyay P, Cao Z, Erdélyi K, Holovac E, Liaudet L, Lee WS, Haskó G, Mechoulam R, Pacher P
Mol Med. 2015 Jan 6;21:38-45
Brain natriuretic peptide is able to stimulate cardiac progenitor cell proliferation and differentiation in murine hearts after birth.
Bielmann C, Rignault-Clerc S, Liaudet L, Li F, Kunieda T, Sogawa C, Zehnder T, Waeber B, Feihl F, Rosenblatt-Velin N
Basic Res Cardiol. 2015 Jan;110(1):455
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CHUV
Rue du Bugnon 46
CH-1011 Lausanne
+41 21 314 1632