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- Pathologie clinique
- Notre équipe
- Pr Ekkehard Hewer
Pr Ekkehard Hewer
Professeur associé Ekkehard Hewer
Médecin chef
Institut universitaire de pathologie
Bugnon 25
CH-1011 Lausanne
Tél. +41 21 314 7140
Fax: +41 21 314 7115
Contact e-mail
Publications
PD-L1 expression in PitNETs: Correlations with the 2022 WHO classification.
Harel E, Hewer E, La Rosa S, Brouland JP, Pitteloud N, Santoni F, Brunner M, Daniel RT, Messerer M, Cossu G
Brain Spine. 2025;5:104171
Lymphoid enhancer-binding factor 1 (LEF1) immunostaining as a surrogate for β-catenin (CTNNB1) mutations.
Hewer E, Fischer PD, Vassella E, Knabben L, Imboden S, Mueller MD, Rau TT, Dettmer MS
J Clin Pathol. 2024 Dec 9
Cytological features of ependymal and choroid plexus tumours.
Egervari K, Hewer E
Cytopathology. 2024 Sep;35(5):556-560
Primary diffuse large B-cell lymphoma of the central nervous system identified with CSF biomarkers.
Loser V, Segot A, de Leval L, Bisig B, Brouland JP, Hewer E, Barcena C, Hottinger AF, Pot C
BMC Neurol. 2024 Jul 22;24(1):250
Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma.
Burgermeister S, Stoykova S, Krebs FS, Zoete V, Mbefo M, Egervari K, Reinhard A, Bisig B, Hewer E
Int J Mol Sci. 2024 Jun 13;25(12)
Characterization of Polarimetric Properties in Various Brain Tumor Types Using Wide-Field Imaging Mueller Polarimetry.
Gros R, Rodriguez-Nunez O, Felger L, Moriconi S, McKinley R, Pierangelo A, Novikova T, Vassella E, Schucht P, Hewer E, Maragkou T
IEEE Trans Med Imaging. 2024 Jun 12;PP
Near-real-time Mueller polarimetric image processing for neurosurgical intervention.
Moriconi S, Rodríguez-Núñez O, Gros R, Felger LA, Maragkou T, Hewer E, Pierangelo A, Novikova T, Schucht P, McKinley R
Int J Comput Assist Radiol Surg. 2024 Jun;19(6):1033-1043
Intraoperative in vivo confocal endomicroscopy of the glioma margin: performance assessment of image interpretation by neurosurgeon users.
Xu Y, On TJ, Abramov I, Restelli F, Belykh E, Mathis AM, Schlegel J, Hewer E, Pollo B, Maragkou T, Quint K, Porter RW, Smith KA, Preul MC
Front Oncol. 2024;14:1389608
EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics.
Hench J, Hultschig C, Brugger J, Mariani L, Guzman R, Soleman J, Leu S, Benton M, Stec IM, Hench IB, Hoffmann P, Harter P, Weber KJ, Albers A, Thomas C, Hasselblatt M, Schüller U, Restelli L, Capper D, Hewer E, Diebold J, Kolenc D, Schneider UC, Rushing E, Della Monica R, Chiariotti L, Sill M, Schrimpf D, von Deimling A, Sahm F, Kölsche C, Tolnay M, Frank S
Acta Neuropathol Commun. 2024 Apr 4;12(1):51
Impact of template-based synoptic reporting on completeness of surgical pathology reports.
Schaad N, Berezowska S, Perren A, Hewer E
Virchows Arch. 2024 Jan;484(1):31-36
Intraoperative in vivo confocal laser endomicroscopy imaging at glioma margins: can we detect tumor infiltration?
Xu Y, Mathis AM, Pollo B, Schlegel J, Maragkou T, Seidel K, Schucht P, Smith KA, Porter RW, Raabe A, Little AS, Sanai N, Agbanyim DC, Martirosyan NL, Eschbacher JM, Quint K, Preul MC, Hewer E
J Neurosurg. 2024 Feb 1;140(2):357-366
Expanding the p.(Arg85Trp) Variant-Specific Phenotype of HNF4A: Features of Glycogen Storage Disease, Liver Cirrhosis, Impaired Mitochondrial Function, and Glomerular Changes.
Grassi M, Laubscher B, Pandey AV, Tschumi S, Graber F, Schaller A, Janner M, Aeberli D, Hewer E, Nuoffer JM, Gautschi M
Mol Syndromol. 2023 Aug;14(4):347-361
Evaluation of MTAP and p16 immunohistochemical deficiency as surrogate marker for CDKN2A/B homozygous deletion in gliomas.
Maragkou T, Reinhard S, Jungo P, Pasquier B, Neuenschwander M, Schucht P, Vassella E, Hewer E
Pathology. 2023 Jun;55(4):466-477
DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations.
Gallon J, Rodriguez-Calero A, Benjak A, Akhoundova D, Maletti S, Amstutz U, Hewer E, Genitsch V, Fleischmann A, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Feng FY, Gillessen S, Ng CKY, Rubin MA, Piscuoglio S
Cancer Res. 2023 Apr 14;83(8):1203-1213
Effects of formalin fixation on polarimetric properties of brain tissue: fresh or fixed?
Gros R, Rodríguez-Núñez O, Felger L, Moriconi S, McKinley R, Pierangelo A, Novikova T, Vassella E, Schucht P, Hewer E, Maragkou T
Neurophotonics. 2023 Apr;10(2):025009
Code-free machine learning for classification of central nervous system histopathology images.
Jungo P, Hewer E
J Neuropathol Exp Neurol. 2023 Feb 21;82(3):221-230
The LUMIERE dataset: Longitudinal Glioblastoma MRI with expert RANO evaluation.
Suter Y, Knecht U, Valenzuela W, Notter M, Hewer E, Schucht P, Wiest R, Reyes M
Sci Data. 2022 Dec 15;9(1):768
HHV8-negative primary effusion-based large B-cell lymphoma in a patient with chronic myeloid leukemia, BCR::ABL1-positive under dasatinib treatment: Report of a new case and literature review.
Christe L, Veloza L, Gros L, Bisig B, Blum S, Hewer E, de Leval L
Diagn Cytopathol. 2022 Dec;50(12):E351-E356
Intraoperative confocal laser endomicroscopy for brain tumors - potential and challenges from a neuropathological perspective.
Maragkou T, Quint K, Pollo B, Hewer E
Free Neuropathol. 2022 Jan;3
Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV.
Di Liberto G, Egervari K, Kreutzfeldt M, Schürch CM, Hewer E, Wagner I, Du Pasquier R, Merkler D
Brain. 2022 Aug 27;145(8):2730-2741
Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification.
Häni L, Kopcic M, Branca M, Schütz A, Murek M, Söll N, Vassella E, Raabe A, Hewer E, Schucht P
Cancers (Basel). 2022 Jun 27;14(13)
Alterations in homologous recombination repair genes in prostate cancer brain metastases.
Rodriguez-Calero A, Gallon J, Akhoundova D, Maletti S, Ferguson A, Cyrta J, Amstutz U, Garofoli A, Paradiso V, Tomlins SA, Hewer E, Genitsch V, Fleischmann A, Vassella E, Rushing EJ, Grobholz R, Fischer I, Jochum W, Cathomas G, Osunkoya AO, Bubendorf L, Moch H, Thalmann G, Ng CKY, Gillessen S, Piscuoglio S, Rubin MA
Nat Commun. 2022 May 3;13(1):2400
Endoscope-Assisted Extreme Lateral Supracerebellar Infratentorial Approach for Resection of Superior Cerebellar Peduncle Pilocytic Astrocytoma: Technical Note.
Papadimitriou K, Cossu G, Hewer E, Diezi M, Daniel RT, Messerer M
Children (Basel). 2022 Apr 29;9(5)
[Standardized structured reports for gastrointestinal tumors].
Hewer E, Rump A, Langer R
Pathologe. 2022 Feb;43(1):57-62
Oligosarcomas, IDH-mutant are distinct and aggressive.
Suwala AK, Felix M, Friedel D, Stichel D, Schrimpf D, Hinz F, Hewer E, Schweizer L, Dohmen H, Pohl U, Staszewski O, Korshunov A, Stein M, Wongsurawat T, Cheunsuacchon P, Sathornsumetee S, Koelsche C, Turner C, Le Rhun E, Mühlebner A, Schucht P, Özduman K, Ono T, Shimizu H, Prinz M, Acker T, Herold-Mende C, Kessler T, Wick W, Capper D, Wesseling P, Sahm F, von Deimling A, Hartmann C, Reuss DE
Acta Neuropathol. 2022 Feb;143(2):263-281
Erratum zu: Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren.
Hewer E, Rump A, Langer R
Pathologe. 2022 Feb;43(1):63-64
Systematic Investigation of SARS-CoV-2 Receptor Protein Distribution along Viral Entry Routes in Humans.
Bräutigam K, Reinhard S, Galván JA, Wartenberg M, Hewer E, Schürch CM
Respiration. 2022;101(6):610-618
Co-Expression of Nogo-A in Dopaminergic Neurons of the Human Substantia Nigra Pars Compacta Is Reduced in Parkinson's Disease.
Eyer GC, Di Santo S, Hewer E, Andereggen L, Seiler S, Widmer HR
Cells. 2021 Nov 30;10(12)
Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies.
Rodríguez-Núñez O, Schucht P, Hewer E, Novikova T, Pierangelo A
Biomed Opt Express. 2021 Oct 1;12(10):6674-6685
Methylation profiling-based diagnosis of radiologically suspected congenital glioma.
Bräutigam K, Piechowiak E, Slavova N, Mosimann B, Merkler D, Egervari K, Hewer E
Brain Tumor Pathol. 2021 Jan;38(1):78-80
Development of vascularized nerve scaffold using perfusion-decellularization and recellularization.
Wüthrich T, Lese I, Haberthür D, Zubler C, Hlushchuk R, Hewer E, Maistriaux L, Gianello P, Lengelé B, Rieben R, Vögelin E, Olariu R, Duisit J, Taddeo A
Mater Sci Eng C Mater Biol Appl. 2020 Dec;117:111311
Visualization of White Matter Fiber Tracts of Brain Tissue Sections With Wide-Field Imaging Mueller Polarimetry.
Schucht P, Lee HR, Mezouar HM, Hewer E, Raabe A, Murek M, Zubak I, Goldberg J, Kovari E, Pierangelo A, Novikova T
IEEE Trans Med Imaging. 2020 Dec;39(12):4376-4382
Myeloid Sarcoma Mimicking Endocarditis: An Autopsy Case.
Bräutigam K, Hohl A, Hewer E, Langer R, Jakob S
Int J Surg Pathol. 2020 Oct;28(7):774
Radiomics for glioblastoma survival analysis in pre-operative MRI: exploring feature robustness, class boundaries, and machine learning techniques.
Suter Y, Knecht U, Alão M, Valenzuela W, Hewer E, Schucht P, Wiest R, Reyes M
Cancer Imaging. 2020 Aug 5;20(1):55
Seminal vesicle carcinoma presenting with malignant ascites.
Hewer E, Banz Y, Knecht U, Dettmer MS, Vassella E
Diagn Cytopathol. 2020 Aug;48(8):785-786
Lipidised urothelial carcinoma in pleural effusion-A case report.
Saganas C, Hewer E
Diagn Cytopathol. 2020 Jun;48(6):589-590
TERT Promoter Mutation Analysis to Distinguish Glioma From Gliosis.
Hewer E, Phour J, Gutt-Will M, Schucht P, Dettmer MS, Vassella E
J Neuropathol Exp Neurol. 2020 Apr 1;79(4):430-436
Detection of rare reciprocal RUNX1 rearrangements by next-generation sequencing in acute myeloid leukemia.
Flach J, Shumilov E, Joncourt R, Porret N, Tchinda J, Legros M, Scarpelli I, Hewer E, Novak U, Schoumans J, Bacher U, Pabst T
Genes Chromosomes Cancer. 2020 Apr;59(4):268-274
Plaque vulnerability in patients with high- and moderate-grade carotid stenosis - comparison of plaque features on MRI with histopathological findings.
Tapis P, El-Koussy M, Hewer E, Mono ML, Reinert M
Swiss Med Wkly. 2020 Feb 10;150:w20174
Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears.
Hewer E, Schmitt AM
Acta Cytol. 2020;64(4):375-377
Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
Wefers AK, Stichel D, Schrimpf D, Coras R, Pages M, Tauziède-Espariat A, Varlet P, Schwarz D, Söylemezoglu F, Pohl U, Pimentel J, Meyer J, Hewer E, Japp A, Joshi A, Reuss DE, Reinhardt A, Sievers P, Casalini MB, Ebrahimi A, Huang K, Koelsche C, Low HL, Rebelo O, Marnoto D, Becker AJ, Staszewski O, Mittelbronn M, Hasselblatt M, Schittenhelm J, Cheesman E, de Oliveira RS, Queiroz RGP, Valera ET, Hans VH, Korshunov A, Olar A, Ligon KL, Pfister SM, Jaunmuktane Z, Brandner S, Tatevossian RG, Ellison DW, Jacques TS, Honavar M, Aronica E, Thom M, Sahm F, von Deimling A, Jones DTW, Blumcke I, Capper D
Acta Neuropathol. 2020 Jan;139(1):193-209
The Oncologist's Guide to Synoptic Reporting: A Primer.
Hewer E
Oncology. 2020;98(6):396-402
Frequent Diagnostic Under-Grading in Isocitrate Dehydrogenase Wild-Type Gliomas due to Small Pathological Tissue Samples.
Gutt-Will M, Murek M, Schwarz C, Hewer E, Vulcu S, Beck J, Raabe A, Schucht P
Neurosurgery. 2019 Nov 1;85(5):689-694
Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities.
Reinhardt A, Stichel D, Schrimpf D, Koelsche C, Wefers AK, Ebrahimi A, Sievers P, Huang K, Casalini MB, Fernández-Klett F, Suwala A, Weller M, Gramatzki D, Felsberg J, Reifenberger G, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Buslei R, Deckert M, Mawrin C, Hewer E, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Korshunov A, Reuss DE, Sahm F, Jones DTW, Capper D, von Deimling A
Acta Neuropathol Commun. 2019 Oct 28;7(1):163
VLA-4 mediated adhesion of melanoma cells on the blood-brain barrier is the critical cue for melanoma cell intercalation and barrier disruption.
García-Martín AB, Zwicky P, Gruber T, Matti C, Moalli F, Stein JV, Francisco D, Enzmann G, Levesque MP, Hewer E, Lyck R
J Cereb Blood Flow Metab. 2019 Oct;39(10):1995-2010
Ex vivo performance comparison of three percutaneous biopsy needle systems.
Krokidis M, Hungerbühler M, Hewer E, Heverhagen J, von Tengg-Kobligk H
Eur Radiol. 2019 Aug;29(8):4044-4049
Langerhans Cell Histiocytosis of the Adult Cervical Spine: A Case Report and Literature Review.
Schär RT, Hewer E, Ulrich CT
J Neurol Surg A Cent Eur Neurosurg. 2019 Jan;80(1):49-52
Advancing synoptic cancer reports beyond English: the University of Bern/PathoLink approach.
Banz Y, Berezowska S, de Leval L, Rubbia-Brandt L, Tolnay M, Moch H, Perren A, Hewer E
Virchows Arch. 2018 Nov;473(5):655-656
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Reinhardt A, Stichel D, Schrimpf D, Sahm F, Korshunov A, Reuss DE, Koelsche C, Huang K, Wefers AK, Hovestadt V, Sill M, Gramatzki D, Felsberg J, Reifenberger G, Koch A, Thomale UW, Becker A, Hans VH, Prinz M, Staszewski O, Acker T, Dohmen H, Hartmann C, Mueller W, Tuffaha MSA, Paulus W, Heß K, Brokinkel B, Schittenhelm J, Monoranu CM, Kessler AF, Loehr M, Buslei R, Deckert M, Mawrin C, Kohlhof P, Hewer E, Olar A, Rodriguez FJ, Giannini C, NageswaraRao AA, Tabori U, Nunes NM, Weller M, Pohl U, Jaunmuktane Z, Brandner S, Unterberg A, Hänggi D, Platten M, Pfister SM, Wick W, Herold-Mende C, Jones DTW, von Deimling A, Capper D
Acta Neuropathol. 2018 Aug;136(2):273-291
Esophageal Cytology: A Tale of Shish Kebab and Roman Legionaries.
Neppl C, Friedli B, Hewer E
Gastroenterology. 2018 Jul;155(1):e14-e15
Implementation of a 'lean' cytopathology service: towards routine same-day reporting.
Hewer E, Hammer C, Fricke-Vetsch D, Baumann C, Perren A, Schmitt AM
J Clin Pathol. 2018 May;71(5):395-401
DNA methylation-based classification of central nervous system tumours.
Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM
Nature. 2018 Mar 22;555(7697):469-474
H3K27me3 immunostaining for sex determination in the context of presumed tissue misidentification.
Tschui J, Hewer E
Histopathology. 2018 Jan;72(2):358-359
Diagnostic implications of TERT promoter mutation status in diffuse gliomas in a routine clinical setting.
Hewer E, Prebil N, Berezowska S, Gutt-Will M, Schucht P, Dettmer MS, Vassella E
Virchows Arch. 2017 Nov;471(5):641-649
Low co-expression of epidermal growth factor receptor and its chaperone heat shock protein 90 is associated with worse prognosis in primary glioblastoma, IDH-wild-type.
Sartori E, Langer R, Vassella E, Hewer E, Schucht P, Zlobec I, Berezowska S
Oncol Rep. 2017 Oct;38(4):2394-2400
The "don't eat me" signal CD47 is a novel diagnostic biomarker and potential therapeutic target for diffuse malignant mesothelioma.
Schürch CM, Forster S, Brühl F, Yang SH, Felley-Bosco E, Hewer E
Oncoimmunology. 2017;7(1):e1373235
Fatal Outcome of European Tick-borne Encephalitis after Vaccine Failure.
Sendi P, Hirzel C, Pfister S, Ackermann-Gäumann R, Grandgirard D, Hewer E, Nirkko AC
Front Neurol. 2017;8:119
TERT Promoter Mutations but not the Alternative Lengthening of Telomeres Phenotype Are Present in a Subset of Ependymomas and Are Associated With Adult Onset and Progression to Ependymosarcoma.
Brügger F, Dettmer MS, Neuenschwander M, Perren A, Marinoni I, Hewer E
J Neuropathol Exp Neurol. 2017 Jan 1;76(1):61-66
Granulomatous encephalitis: protothecosis excluded?
Hench J, Roschanski N, Hewer E, Rösler U, Lass-Flörl C, Stippich C, Tolnay M, Rusche N, Sonderegger B, Sailer M, Lyrer P, Peters N, Frank S
Histopathology. 2016 Dec;69(6):1082-1084
Two adult cases of massively calcified low-grade glioma: expanding clinical spectrum of an emerging entity.
Hewer E, Knecht U, Ulrich CT
Neuropathology. 2016 Oct;36(5):508-509
Diskogenic microspurs as a major cause of intractable spontaneous intracranial hypotension.
Beck J, Ulrich CT, Fung C, Fichtner J, Seidel K, Fiechter M, Hsieh K, Murek M, Bervini D, Meier N, Mono ML, Mordasini P, Hewer E, Z'Graggen WJ, Gralla J, Raabe A
Neurology. 2016 Sep 20;87(12):1220-6
Adult anaplastic pilocytic astrocytoma - a diagnostic challenge? A case series and literature review.
Fiechter M, Hewer E, Knecht U, Wiest R, Beck J, Raabe A, Oertel MF
Clin Neurol Neurosurg. 2016 Aug;147:98-104
Reply: Does morphological assessment have a role in classifying oligoastrocytoma as 'oligodendroglial' versus 'astrocytic'? Or - who's afraid of the … liger?
Hewer E, Dettmer MS, Vajtai I
Histopathology. 2016 Jun;68(7):1115-7
Combined ATRX/IDH1 immunohistochemistry predicts genotype of oligoastrocytomas.
Hewer E, Vajtai I, Dettmer MS, Berezowska S, Vassella E
Histopathology. 2016 Jan;68(2):272-8
Suprasellar chordoid neoplasm with expression of thyroid transcription factor 1: evidence that chordoid glioma of the third ventricle and pituicytoma may form part of a spectrum of lineage-related tumors of the basal forebrain.
Hewer E, Beck J, Kellner-Weldon F, Vajtai I
Hum Pathol. 2015 Jul;46(7):1045-9
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
Pajtler KW, Witt H, Sill M, Jones DT, Hovestadt V, Kratochwil F, Wani K, Tatevossian R, Punchihewa C, Johann P, Reimand J, Warnatz HJ, Ryzhova M, Mack S, Ramaswamy V, Capper D, Schweizer L, Sieber L, Wittmann A, Huang Z, van Sluis P, Volckmann R, Koster J, Versteeg R, Fults D, Toledano H, Avigad S, Hoffman LM, Donson AM, Foreman N, Hewer E, Zitterbart K, Gilbert M, Armstrong TS, Gupta N, Allen JC, Karajannis MA, Zagzag D, Hasselblatt M, Kulozik AE, Witt O, Collins VP, von Hoff K, Rutkowski S, Pietsch T, Bader G, Yaspo ML, von Deimling A, Lichter P, Taylor MD, Gilbertson R, Ellison DW, Aldape K, Korshunov A, Kool M, Pfister SM
Cancer Cell. 2015 May 11;27(5):728-43
Consistent nuclear expression of thyroid transcription factor 1 in subependymal giant cell astrocytomas suggests lineage-restricted histogenesis.
Hewer E, Vajtai I
Clin Neuropathol. 2015 May-Jun;34(3):128-31
Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles.
Koelsche C, Hovestadt V, Jones DT, Capper D, Sturm D, Sahm F, Schrimpf D, Adeberg S, Böhmer K, Hagenlocher C, Mechtersheimer G, Kohlhof P, Mühleisen H, Beschorner R, Hartmann C, Braczynski AK, Mittelbronn M, Buslei R, Becker A, Grote A, Urbach H, Staszewski O, Prinz M, Hewer E, Pfister SM, von Deimling A, Reuss DE
Brain Pathol. 2015 Mar;25(2):202-8
Complete pain relief after bevacizumab in a patient with neurofibromatosis type 2.
Kollár A, Hewer E, Kellner-Weldon F, Ochsenbein A
Acta Oncol. 2015 Feb;54(2):280-3
Glioma-like proliferation in a cortical hamartoma of tuberous sclerosis complex.
Hewer E, Mariani L, Vajtai I
Brain Tumor Pathol. 2015 Jan;32(1):76-8
Multiple cerebral lesions in a 60-year-old female patient with a history of liver transplantation.
Hewer E, Kellner-Weldon F, Abu-Isa J, Schmitt AM
Neuropathology. 2014 Aug;34(4):425-7
Polymorphous oligodendroglioma of Zülch revisited: a genetically heterogeneous group of anaplastic gliomas including tumors of bona fide oligodendroglial differentiation.
Hewer E, Beck J, Murek M, Kappeler A, Vassella E, Vajtai I
Neuropathology. 2014 Aug;34(4):323-32
Desmoplastic small round cell tumor: a rare cause of a progressive brachial plexopathy.
Mathys J, Vajtai I, Vögelin E, Zimmermann DR, Ozdoba C, Hewer E
Muscle Nerve. 2014 Jun;49(6):922-7
Anaplastic oligodendroglioma arising from the brain stem and featuring 1p/19q co-deletion.
Hewer E, Beck J, Vassella E, Vajtai I
Neuropathology. 2014 Feb;34(1):32-8
Early re-do surgery for glioblastoma is a feasible and safe strategy to achieve complete resection of enhancing tumor.
Schucht P, Murek M, Jilch A, Seidel K, Hewer E, Wiest R, Raabe A, Beck J
PLoS One. 2013;8(11):e79846
Rosette-forming glioneuronal tumor of the cerebellum in statu nascendi: an incidentally detected diminutive example indicates derivation from the internal granule cell layer.
Thommen F, Hewer E, Schäfer SC, Vassella E, Kappeler A, Vajtai I
Clin Neuropathol. 2013 Sep-Oct;32(5):370-6
Cytokeratin-positive epithelioid gastrointestinal stromal tumor of the stomach - a comment on "gastric undifferentiated carcinoma with diffuse c-kit overexpression and focal neuroendocrine differentiation".
Hewer E, Genitsch V, Schäfer SC, Vajtai I
Pathol Res Pract. 2013 Jul;209(7):467-8
Myoepithelioma of the cerebellopontine angle: a previously not documented benign salivary gland-type neoplasm within the cranium.
Vajtai I, Hewer E, Neuenschwander M, Schäfer SC, Kappeler A, Lukes A
Clin Neuropathol. 2013 May-Jun;32(3):176-82
Intraosseous traumatic neuroma of the lumbar spine: a previously unrecognized form of vertebral pseudotumor.
Guevara C, Seidel U, Hewer E, Vajtai I
Clin Neuropathol. 2013 May-Jun;32(3):189-91
"Leiomyomatoid angiomatous neuroendocrine tumor" (LANT) of the pituitary reflects idiosyncratic angiogenesis in adenomas of the gonadotroph cell lineage.
Schürch C, Birrer M, Estella I, Kappeler A, Hewer E, Vajtai I
Pathol Res Pract. 2013 Mar;209(3):155-60
Delayed diagnosis of cryptococcal meningoencephalitis due to negative cryptococcal antigen test.
Kessler B, Bally F, Hewer E, Sendi P
BMJ Case Rep. 2013 Jan 29;2013
Sarcomatous evolution of oligodendroglioma ("oligosarcoma"): confirmatory report of an uncommon pattern of malignant progression in oligodendroglial tumors.
Vajtai I, Vassella E, Hewer E, Kappeler A, Reinert MM
Pathol Res Pract. 2012 Dec 15;208(12):750-5
Plexiform hybrid granular cell tumor/perineurioma: a novel variant of benign peripheral nerve sheath tumor with divergent differentiation.
Matter A, Hewer E, Kappeler A, Fleischmann A, Vajtai I
Pathol Res Pract. 2012 May 15;208(5):310-4
Meningial perineurioma: a benign peripheral nerve sheath tumor in a previously unrecognized central nervous system location, mimicking meningioma.
Vajtai I, Hewer E, Andres R, Neuenschwander M, Kappeler A, Gugger M
Pathol Res Pract. 2011 Sep 15;207(9):592-6
Spindle cell oncocytoma of the pituitary gland with follicle-like component: organotypic differentiation to support its origin from folliculo-stellate cells.
Vajtai I, Beck J, Kappeler A, Hewer E
Acta Neuropathol. 2011 Aug;122(2):253-8
Atypical prion protein conformation in familial prion disease with PRNP P105T mutation.
Polymenidou M, Prokop S, Jung HH, Hewer E, Peretz D, Moos R, Tolnay M, Aguzzi A
Brain Pathol. 2011 Mar;21(2):209-14
Mutations in the Nijmegen breakage syndrome gene in medulloblastomas.
Huang J, Grotzer MA, Watanabe T, Hewer E, Pietsch T, Rutkowski S, Ohgaki H
Clin Cancer Res. 2008 Jul 1;14(13):4053-8
Transcranial ultrasound of the basal ganglia in sporadic Creutzfeldt-Jakob disease.
Martin M, Thomas T, Ekkehard H, Katharina S
J Neuroimaging. 2008 Apr;18(2):154-7
Myopathology of non-infectious inflammatory myopathies - the current status.
Hewer E, Goebel HH
Pathol Res Pract. 2008;204(9):609-23
Rue du Bugnon 25
CH-1011 Lausanne, Vaud, Suisse
+41 21 314 7111
Rue du Bugnon 25
CH-1011 Lausanne, Vaud, Suisse
+41 21 314 7111