Neuro-oncology

Dr Andreas Hottinger

The unit’s physicians are also internationally recognised clinical researchers. They are actively involved in developing new strategies to treat patients who suffer from brain tumours. Our patients therefore have access to the most recent treatments and can participate in clinical studies. To date, 30 clinical studies for patients suffering from brain tumours have been carried out in the unit.

Experimental research

The Neuro-oncology unit works in close collaboration with the Laboratory of tumor biology and genetics (head: Prof. Monika Hegi) and with Prof. Doug Hanahan’s team (EPFL) to analyse and understand the molecular mechanisms involved in the formation of brain tumours.

Collaborations

In clinical research, ties have been established with numerous Swiss institutions (Universities of Geneva and Zurich, EPFL, SAKK, the Swiss Group for Clinical Cancer Research) as well as international institutions (European Organization for Research and Treatment of Cancer (EORTC).

Publications

• Hottinger et al. Delayed but Complete Response following Oral Temozolomide Treatment in Melanoma Leptomeningeal Carcinomatosis. Case Rep Oncol. 2011 4:211-5.
• Hottinger et al. YKL-40 and MMP-9 as serum markers for patients with primary central nervous system lymphoma. Ann Neurol. 2011 Jul;70(1):163-9. doi: 10.1002/ana.22360
• Hottinger AF, Khakoo Y. Neurooncology of familial cancer syndromes. J Child Neurol. 2009 24:1526-35.
• Hottinger et al. Neurological outcome of long-term glioblastoma survivors. J Neurooncol. 2009 95:301-5.
• Hottinger et al. Salvage whole brain radiotherapy for recurrent or refractory primary CNS lymphoma. Neurology. 2007 69:1178-82.