Understanding proteostasis in blood cancer cells: our team investigates how differences in protein synthesis and degradation in cancer cells can be exploited for therapeutic purposes.
Our major research interest is the understanding of the interplay between platelet activation and coagulation, and its clinical relevance.
The overall goal of our research is to develop novel targeted immunotherapies for patients with hematologic malignancies.
Our goal is to gain deeper insights into the bone marrow microenvironment and how it can be modulated to enhance blood cell progenitor function in the context of aging and bone marrow failure.
We study human CD8 T-cell responses to self-(tumor) and foreign (viral) antigens with the aim to advance our knowledge of T cell-mediated protection from human disease and to improve T cell-based therapies against cancer.